PUBLICATIONS

PREPRINTS (trainees are underlined)

  • Johnston MJ, Nikolic A, Ninkovic N, Guilhamon P, Cavalli FMG, Seaman S, Zemp FJ, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida MM, Coutinho FJ, Ma Y, Mungall AJ, Moore R, Marra MA, Taylor MD, Dirks PB, Pugh TJ, Morrissy AS, St Croix B, Mahoney DJ, Lupien M, Gallo M. High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma. bioRχiv doi: https://doi.org/10.1101/442277.
  • Hoffman M, Gillmor AH, Kunz DJ, Johnston MJNikolic A, Karta K, King J, Ellestad K, Dang NH, Cavalli FMG, Kushida MM, Coutinho FJ, Luu B, Ma Y, Mungall AJ, Moore R, Marra MA, Taylor MD, Pugh TJ, Dirks PB, Senger DL, Simons BD, Chan JA, Morrissy AS, Gallo M. Subclonal architecture, evolutionary trajectories and patterns of germline variants in pediatric glioblastoma. bioRχiv doi: https://doi.org/10.1101/434241.

 

ACCEPTED PAPERS

  • Lee D, Leão R, Komosa M, Gallo M, Zhang CH, Lipman T, Remke M, Heidari A, Nunes NM, Apolónio JD, De Mello RA, Dias J, Huntsman D, Hermanns T, Wild PJ, Vanner R, Zadeh G, Karamchandani J, Das S, Taylor MD, Hawkins CE, Wasserman JD, Figueiredo A, Hamilton RJ, Minden MD, Wani K, Diplas B, Yan H, Aldape K, Akbari MR, Danesh A, Pugh TJ, Dirks PB, Castelo-Branco P, Tabori U (2019) DNA hypermethylation within TERT promoter upregulates TERT expression in cancer. Journal of Clinical Investigation. PMID: 30358567.
  • Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida M, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, Luu B, Carles A, Moksa M, Rastegar N, Head R, Dolma S, Prinos P, Cusimano MD, Das S, Bernstein M, Arrowsmith CH, Mungall AJ, Moore RA, Ma Y, Gallo M, Lupien M, Pugh TJ, Taylor MD, Hirst M, Eaves CJ, Simons BD, and Dirks PB (2017) Cell fate mapping of human glioblastoma reveals an invariant stem cell hierarchy. Nature. PMID: 28854171.
  • Gallo M*, Dirks PB* (2016) Global chromatin architecture defines functional cancer hierarchies. Cell Cycle 15: 2093-2094. PMID: 27247183. *Corresponding authors.
  • Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida M, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones D, Lupien M*, Dirks PB* (2015) MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3.3 and globally reorganizing chromatin. Cancer Cell 28: 1-15. PMID: 26626085. *Co-corresponding authors.
  • Vanner RJ, Remke M, Gallo M, Selvadurai HJ, Coutinho FJ, Lee L, Kushida M, Head R, Morrissy S, Zhu X, Aviv T, Voisin V, Clarke ID, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Marra MA, Malkin D, Northcott PA, Kool M, Pfister SM, Bader G, Hochedlinger K, Korshunov A, Taylor MD, Dirks PB (2014) Quiescent Sox2+ cells drive hierarchical growth and relapse in Sonic hedgehog subgroup medulloblastoma. Cancer Cell 26: 33-47. PMID: 24954133.
  • Mack SC*, Witt H*, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, Pugh TJ, Ryzhova M, Wani KM, Shih DJ, Head R, Remke M, Bailey SD, Zichner T, Faria CC, Barszczyk M, Stark S, Seker-Cin H, Hutter S, Johann P, Bender S, Hovestadt V, Tzaridis T, Dubuc AM, Northcott PA, Peacock J, Bertrand KC, Agnihotri S, Cavalli FM, Clarke I, Nethery-Brokx K, Creasy CL, Verma SK, Koster J, Wu X, Yao Y, Milde T, Sin-Chan P, Zuccaro J, Lau L, Pereira S, Castelo-Branco P, Hirst M, Marra MA, Roberts SS, Fults D, Massimi L, Cho YJ, Van Meter T, Grajkowska W, Lach B, Kulozik AE, von Deimling A, Witt O, Scherer SW, Fan X, Muraszko KM, Kool M, Pomeroy SL, Gupta N, Phillips J, Huang A, Tabori U, Hawkins C, Malkin D, Kongkham PN, Weiss WA, Jabado N, Rutka JT, Bouffet E, Korbel JO, Lupien M, Aldape KD, Bader GD, Eils R, Lichter P, Dirks PB, Pfister SM, Korshunov A**, Taylor MD** (2014) Epigenomic alterations define lethal CIMP positive ependymomas of infancy. Nature 506: 445-450. PMID: 24553142. *These authors contributed equally. **Co-corresponding authors.
  • Kleinman CL, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Khuong Quang D-A, Adoue V, Busche S, Caron M, Djambazian H, Bemmo A, Fontebasso AM, Spence T, Schwartzentruber J, Albrecht S, Hauser P, Garami M, Klekner A, Bognar L, Montes J-L, Staffa A, Montpetit A, Berube, P, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel PM, Duchaine T, Perotti C, Fleming A, Faury D, Remke M, Gallo M, Dirks P, Taylor MD, Sladek R, Pastinen T, Chan JA, Huang A, Majewski J, Jabado N (2014) Fused transcripts of TTYH1 and the C19MC microRNA cluster reawaken expression of an early development brain-specific DNMT3B and characterize the embryonal brain tumour ETMR. Nature Genetics 46: 39-44. PMID: 24316981.
  • Gallo M, Ho J, Coutinho FJ, Vanner R, Lee L, Head R, Ling EKM, Clarke ID, Dirks PB (2013) A tumorigenic MLL-Homeobox network in human glioblastoma stem cells.  Cancer Research 73: 417-427. PMID: 23108137.